Fatigue is a frequent symptom in patients with primary Sjögren's syndrome (pSS) and can be a cause of or be associated with sleep disorders.
Here we show a research study that was done to assess the sleep quality of people with Sjogren's and its relationship with fatigue and disease activity. The study was named 'Correlation of sleep quality with fatigue and disease activity among patients with primary Sjögren's syndrome: a cross-sectional study' and was conducted in different universities in Brazil in 2019.
It was an analytical observational study conducted at an exercise psychobiology laboratory.
The study says that the participants were all taking longer to get to sleep and were awake for longer during sleep than a person without sjogren's. The researchers said these sleep issues contribute to day time fatigue in sjogren's.
Methods:
Sleep quality was evaluated using the Pittsburg sleep quality index (PSQI) and actigraphy.
Fatigue was evaluated through the Profile of Fatigue and Discomfort - Sicca Symptoms Inventory (PROFAD-SSI-SF) and a visual analogue scale for fatigue (VAS-fatigue).
Disease activity was evaluated using a visual analogue scale for pain (VAS-pain), EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) and Disease Activity Index (ESSDAI).
Results:
- A total of 50 female patients with pSS, of average age 56.4 years, were included in the study; 80% of these women presented with low disease activity.
- 74% had poor sleep as shown in the total PSQI score.
- The actigraphy showed mean sleep latency of 26.2 minutes and mean nightly awakening of 48.2 minutes. Normal adult mean sleep latency is between 10 and 20 minutes.
Actigraphy involves acquisition of data using a movement sensor worn continuously on the nondominant wrist, typically for a week or more.
Sleep latency is the amount of time it takes you to go from being fully awake to sleeping.
Conclusion: The study provides important information regarding correlations between sleep disorders and disease activity. There is a need for proper control over disease activity and for development of strategies to help patients to sleep better in order to diminish their fatigue.
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