Fatigue occurs in 70% of people with sjogren's and significantly impacts quality of life. But with so many affected, what can we do about it? This study shows that there are some treatment options already available and some others in the pipeline.
The systems involved with fatigue in sjogren's syndrome (SS) are still poorly understood, but it appears that the pathways signaling fatigue are more associated with cell protection and defense than with pro-inflammatory pathways.
There are no established pharmacological treatment options for fatigue in SS. So far, exercise and neuromodulation techniques have shown positive effects on fatigue in SS.
This study reviews fatigue in pSS, primary Sjogren's Syndrome, with special attention to outcome measures, biomarkers, and possible treatment options. Here I have summarised some of the study:
- The mechanisms involved in pSS fatigue are still not fully understood.
- Hydroxychloroquine, DHEA, and rituximab failed to improve fatigue in controlled studies
- Exercise and neuromodulation techniques have shown positive effects on fatigue in pSS (primary sjogren's syndrome)
- There is promise for cognitive behavioral interventions
- Studies are being done to provide clinical proof that acupuncture has beneficial effects on pSS.
- A non-invasive vagus nerve stimulation device may reduce clinical symptoms of fatigue and sleepiness
So have you tried acupuncture for your symptoms of fatigue in Sjogren's syndrome? How about CBT also known as Cognitive-behavior Therapy? What do you know about the vagus nerve stimulation device? Most of these approaches entail quite a monetary commitment to have a course of treatment or have you been able to access these for free?
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